Recombinant STAT1 Antibody

抗体

信号转导与转录激活因子1抗体 | 信号转导与转录激活因子1单克隆抗体 | 信号转导与转录激活因子1重组单克隆抗体 | STAT1抗体 | STAT1单克隆抗体 | STAT1重组单克隆抗体

CANDF7 | DKFZp686B04100 | ISGF-3 | ISGF-3,91kD | signal transducer and activator of transcription 1, 91kDa | signal transducer and activator of transcription-1 | STAT1 | STAT91 | Signal transducer and activator of transcription 1 91kD antibody | CANDF7 an

Liquid

Ab129384-10μl

10μl

重组

见COA

-20°C储存,避免反复冻融

超低温冰袋运输

短期储存2-8℃（1-2周）；长期储存-20℃（24个月）；收货后建议分装，避免反复冻融。

10mM PBS, 150mM NaCl, 50% Glycerol, 0.05% BSA, 0.02% Sodium azide, pH7.4

0.02% Sodium azide

Signal transducer and activator of transcription that mediates signaling by interferons (IFNs). Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state. In response to type II IFN (IFN-gamma), STAT1 is tyrosine- and serine-phosphorylated. It then forms a homodimer termed IFN-gamma-activated factor (GAF), migrates into the nucleus and binds to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state.

A synthetic peptide derived from human STAT1 (AA 700-750)

兔(Rabbit)

人(Human), 小鼠(Mouse) | 人(Human),小鼠(Mouse)

STAT1

WB: HeLa, HEK293, MCF7, K562, HT-29, U-2 OS and NIH/3T3 cell lysates.

150 kDa

Unconjugated

Rabbit IgG

重组抗体

kappa

Protein A purified

Whole IgG