Recombinant STAT3 Antibody

抗体

抗STAT3抗体 | Anti-STAT3抗体 | STAT3抗体 | 信号传导转录激活因子3(STAT3)单克隆抗体

APRFMGC16063 | DNA-binding protein APRF | FLJ20882 | HIES | signal transducer and activator of transcription 3 (acute-phase responsefactor) | signal transducer and activator of transcription 3 | STAT3 | 1110034C02Rik antibody | Acute-phase response factor

Liquid

Ab129421-10μl

10μl

重组

见COA

-20°C储存,避免反复冻融

超低温冰袋运输

4°C 短期储存（1-2 周）。-20°C下长期保存（24个月）。收货后建议分装。避免冷冻/解冻循环。

10mM PBS, 150mM NaCl, 50% Glycerol, 0.05% BSA, 0.02% Sodium azide, pH 7.4

0.02% Sodium azide

Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors. Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene (PubMed:17344214). May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. Involved in cell cycle regulation by inducing the expression of key genes for the progression from G1 to S phase, such as CCND1 (PubMed:17344214). Mediates the effects of LEP on melanocortin production, body energy homeostasis and lactation (By similarity). May play an apoptotic role by transctivating BIRC5 expression under LEP activation (PubMed:18242580). Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity.

A synthetic peptide derived from human STAT3 (AA 670-700)

兔(Rabbit)

人(Human), 大鼠(Rat), 小鼠(Mouse) | 人(Human),大鼠(Rat),小鼠(Mouse)

STAT3

WB: Mouse heart, HT-1080, HeLa, HEK293, A375, A431, NIH/3T3 and C6 lysates. IHC: Rat brain, Human astrocytoma, Human Hodgkin's lymphoma tissues. IF/ICC: HeLa cells.

150 kDa

Unconjugated

Rabbit IgG

重组抗体

kappa

Protein A purified

Whole IgG