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名称
Recombinant TBP Antibody
分子类型
抗体
别名
TATA结合蛋白内参抗体 | TBP抗体 | TBP重组抗体 | TBP单克隆抗体
英文别名
GTF2D antibody | GTF2D1 antibody | HDL4 antibody | MGC117320 antibody | MGC126054 antibody | MGC126055 antibody | SCA17 antibody | TATA binding factor antibody | TATA box factor antibody | TATA sequence binding protein antibody | TATA sequence-binding pro
物理外观
Liquid
货号
Ab130263-10μl
包装规格
10μl
级别
重组
浓度
见COA
储存温度
-20°C储存,避免反复冻融
运输条件
超低温冰袋运输
稳定性与储存
4°C 短期储存(1-2 周)。-20°C下长期保存(24个月)。收货后建议分装。避免冷冻/解冻循环。
储存缓冲液
10mM PBS, 150mM NaCl, 50% Glycerol, 0.05% BSA, 0.02% Sodium azide, pH 7.4
防腐剂
0.02% Sodium azide
生化机理
The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. The TFIID complex structure can be divided into 3 modules TFIID-A, TFIID-B, and TFIID-C. TBP is a general transcription factor that functions at the core of the TFIID complex.During assembly of the core PIC on the promoter, as part of TFIID, TBP binds to and also bends promoter DNA, irrespective of whether the promoter contains a TATA box. Component of a BRF2-containing transcription factor complex that regulates transcription mediated by RNA polymerase III. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.
免疫原
A synthetic peptide derived from human TBP (AA 235-294).
宿主种属
兔(Rabbit)
种属反应性
人(Human), 大鼠(Rat), 小鼠(Mouse) | 人(Human),大鼠(Rat),小鼠(Mouse)
特异性
TBP
阳性对照
WB: MCF7 cell lysate.
SDS-PAGE
150 kDa
偶联
Unconjugated
亚型
Rabbit IgG
克隆类型
重组抗体
轻链亚型
kappa
纯化方法
Protein A purified
Format
Whole IgG
危险属性
「暂无危险属性」
上下游信息
「暂无上下游信息」
技术文档
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相关文章
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Recombinant TBP Antibody 重组 10μl
品牌:阿拉丁
货号:Ab130263-10μl
级别: 重组
货期:30天
已售 196 件
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运费:0 元
规格:
10μl
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