Recombinant TRIM24 Antibody

抗体

三重基序蛋白24(TRIM24)重组抗体

E3 ubiquitin protein ligase TRIM24 antibody | E3 ubiquitin-protein ligase Trim24 antibody | hTIF1 antibody | PTC6 antibody | RING finger protein 82 antibody | RNF82 antibody | TF1A antibody | TIF1 alpha antibody | TIF1 antibody | TIF1-alpha antibody | TIF

Liquid

Ab132474-10μl

10μl

重组

见COA

-20°C储存,避免反复冻融

超低温冰袋运输

4°C 运输。送达后，等分并储存于 -20°C。避免冷冻/解冻循环。

10mM PBS, 150mM NaCl, 50% Glycerol, 0.05% BSA, 0.02% Sodium azide, pH 7.4

0.02% Sodium azide

Transcriptional coactivator that interacts with numerous nuclear receptors and coactivators and modulates the transcription of target genes. Interacts with chromatin depending on histone H3 modifications, having the highest affinity for histone H3 that is both unmodified at 'Lys-4' (H3K4me0) and acetylated at 'Lys-23' (H3K23ac). Has E3 protein-ubiquitin ligase activity. Promotes ubiquitination and proteasomal degradation of p53/TP53. Plays a role in the regulation of cell proliferation and apoptosis, at least in part via its effects on p53/TP53 levels. Up-regulates ligand-dependent transcription activation by AR, GCR/NR3C1, thyroid hormone receptor (TR) and ESR1. Modulates transcription activation by retinoic acid (RA) receptors, including RARA. Plays a role in regulating retinoic acid-dependent proliferation of hepatocytes.

A synthetic peptide derived from human TRIM24 (AA 405-455)

兔(Rabbit)

人(Human), 小鼠(Mouse) | 人(Human),小鼠(Mouse)

TRIM24

WB: HeLa, HEK293, Hep G2 and NIH/3T3 cell lysates.

150 kDa

Unconjugated

Rabbit IgG

重组抗体

kappa

Protein A purified

Whole IgG