ZO1 tight junction Antibody

抗体

ZO1 tight junction抗体 | ZO1 tight junction多克隆抗体 | 紧密连接蛋白1抗体 | 紧密连接蛋白1多克隆抗体

Tight junction protein 1 antibody | Tight junction protein ZO-1 antibody | Tight junction protein ZO1 antibody | TJP1 antibody | zo-1 antibody | Zo1 antibody | ZO1_HUMAN antibody | Zona occludens 1 antibody | Zona occludens 1 protein antibody | Zona occlu

Liquid

Ab135462-10μl

10μl

无载体

见COA

-20°C储存,避免反复冻融

超低温冰袋运输

短期储存4℃（1-2周）；长期储存-20℃（12个月）；收货后建议分装，避免反复冻融。

0.42% Potassium phosphate, 0.87% Sodium chloride, 30% Glycerol, 0.01% Sodium azide, pH 7.3

0.01% Sodium azide

TJP1, TJP2, and TJP3 are closely related scaffolding proteins that link tight junction (TJ) transmembrane proteins such as claudins, junctional adhesion molecules, and occludin to the actin cytoskeleton. Forms a multistranded TJP1/ZO1 condensate which elongates to form a tight junction belt, the belt is anchored at the apical cell membrane via interaction with PATJ. The tight junction acts to limit movement of substances through the paracellular space and as a boundary between the compositionally distinct apical and basolateral plasma membrane domains of epithelial and endothelial cells. Necessary for lumenogenesis, and particularly efficient epithelial polarization and barrier formation. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells. Plays an important role in podosome formation and associated function, thus regulating cell adhesion and matrix remodeling. With TJP2 and TJP3, participates in the junctional retention and stability of the transcription factor DBPA, but is not involved in its shuttling to the nucleus. May play a role in mediating cell morphology changes during ameloblast differentiation via its role in tight junctions.

Recombinant full length protein of human ZO1 tight junction.

兔(Rabbit)

人(Human), 小鼠(Mouse) | 人(Human),小鼠(Mouse)

ZO1 tight junction

WB: C2C12 and HEK293 cell lysates. IF/ICC: MCF7 cells.

150 kDa

Unconjugated

Rabbit IgG

多克隆抗体

Immunogen affinity purified

Whole IgG