Bcl-XL Mouse mAb

抗体

抗凋亡抑制基因BCL-XL抗体；Bcl-XL 小鼠单克隆抗体 | Anti-Bcl-XL抗体 | Bcl-XL小鼠单克隆抗体 | Bcl-XL小鼠单抗 | B细胞超大淋巴瘤 | Bcl-XL抗体 | 小鼠抗人Bcl-XL单克隆抗体

Apoptosis regulator Bcl X antibody | Apoptosis regulator Bcl-X antibody | Apoptosis regulator BclX antibody | B cell lymphoma 2 like antibody | B2CL1_HUMAN antibody | Bcl 2 like 1 protein antibody | Bcl X antibody | Bcl xL antibody | BCL XL/S antibody | B

Liquid

Ab156202-50μl

50μL

无载体

≥95%(SDS-PAGE)

-20°C储存,避免反复冻融

超低温冰袋运输

短期储存2-8℃（1-2周）；长期储存-20℃（24个月）；收货后建议分装，避免反复冻融.

PBS, pH 7.4

Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis. Isoform Bcl-X(L) also regulates presynaptic plasticity, including neurotransmitter release and recovery, number of axonal mitochondria as well as size and number of synaptic vesicle clusters. During synaptic stimulation, increases ATP availability from mitochondria through regulation of mitochondrial membrane ATP synthase F1F0 activity and regulates endocytic vesicle retrieval in hippocampal neurons through association with DMN1L and stimulation of its GTPase activity in synaptic vesicles. May attenuate inflammation impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release. Isoform Bcl-X(S) promotes apoptosis.

Recombinant protein corresponding to human Bcl-XL

小鼠(Mouse)

人(Human)

Human Bcl-XL

Flow Cytometry: Jurkat cells

150.0 KDa

Unconjugated

Mouse IgG1 | IgG2b

单克隆抗体

kappa

Protein A purified

IJ02/2C6 | AB04/4D7

Whole IgG