Caspase-9 Mouse mAb

抗体

半胱氨酸天冬氨酸蛋白酶9 | 半胱氨天冬酶9抗体 | Caspase-9/CASP9 抗体 | CASP9 抗体

APAF-3 antibody | APAF3 antibody | Apoptosis related cysteine peptidase antibody | Apoptotic protease Mch-6 antibody | Apoptotic protease-activating factor 3 antibody | CASP-9 antibody | CASP9 antibody | CASP9_HUMAN antibody | Caspase 9 apoptosis related

Ab183845-10μl

10μl

无载体

≥95%(SDS-PAGE)

-20°C储存,避免反复冻融

超低温冰袋运输

短期储存2-8℃ (1-2周); 长期储存-20℃ (24个月); 收货后建议分装，避免反复冻融.

PBS, pH 7.2

Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates effector caspases caspase-3 (CASP3) or caspase-7 (CASP7). Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Cleaves BIRC6 following inhibition of BIRC6-caspase binding by DIABLO/SMAC.

Recombinant protein corresponding to Human Caspase-9

小鼠(Mouse)

人(Human)

Human Caspase-9

WB: HeLa, HepG2, K562 and HEK293 whole cell lysates Flow Cytometry: K562 cells IF/ICC: HeLa cells

150.0 KDa

Unconjugated

Mouse IgG2b

单克隆抗体

kappa

Protein A purified

GH01/4B9

Whole IgG