SIRP alpha/CD172a Rat mAb (AF488)

抗体

信号调节蛋白α(SIRPa)抗体 | SIRP alpha/CD172a抗体

Bit | SIRP | SHP-1 | Ptpns1 | Idd13.2 | BITbrain-immunoglobulin-like molecule with tyrosine-based activation motifs | Brain Ig-like molecule with tyrosine-based activation motifs | CD172 antigen-like family member A | CD172a antigen | CD172a | Inhibitory

Ab191790-10μg

10μg

已验证

0.5 mg/mL

2-8°C储存,避光,禁止冷冻

冰袋运输

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300.

0.05% Proclin300

Immunoglobulin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May play a key role in intracellular signaling during synaptogenesis and in synaptic function (By similarity). Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin. Mediates negative regulation of phagocytosis, mast cell activation and dendritic cell activation. CD47 binding prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells.

Mouse brain membrane protein

大鼠(Rat)

小鼠(Mouse)

SIRP alpha/CD172a

Flow: C57BL/6 mouse bone marrow cells.

AF488

Rat IgG1

单克隆抗体

kappa

Protein A purified

P84

Blue Laser(488nm)

525nm

Ex:490nm;Em:525nm

Whole IgG