NCI m972 (anti-CD22)

抗体

CD22抗体 | CD22单克隆抗体 | CD22药靶抗体 | Siglec-2抗体 | Siglec-2单克隆抗体 | Siglec-2药靶抗体

B cell receptor CD22 precursor antibody | B lymphocyte cell adhesion molecule antibody | B-cell receptor CD22 antibody | B-lymphocyte cell adhesion molecule antibody | BL CAM antibody | BL-CAM antibody | BLCAM antibody | CD 22 antibody | CD22 antibody | C

Ab209824-100μg

100μg

无动物源

≥95%(SDS-PAGE&SEC-HPLC)

-80℃储存,避免反复冻融

超低温冰袋运输

Store at -80℃ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle.

Supplied as a 0.22μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0

No

Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.

人(Human)

人(Human)

CD22

144.3 kDa

Unconjugated

Human IgG1

重组抗体

kappa

Protein A purified

Whole IgG