Recombinant CD11b Antibody

抗体

CD11抗原样家族成员B | 整合素alpha M（ITGAM） | 整合素α M单克隆抗体 | ITGAM 抗体 | Anti-CD11b抗体 | CD11b抗体 | CD11b单抗

antigen CD11b (p170) | CD11 antigen-like family member B | CD11b antigen | CD11b | Cell surface glycoprotein MAC-1 subunit alpha | Complement component 3 receptor 3 subunit | Mo1, alpha subunit antibody | MO1A antibody | Neutrophil adherence receptor alph

Ab210604-10μg

10μg

无动物源

≥95%(SDS-PAGE)

-20°C储存,避免反复冻融

超低温冰袋运输

Store at 4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.

PBS, pH 7.4

Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens (By similarity). It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin ITGAM/ITGB2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. Regulates neutrophil migration. In association with beta subunit ITGB2/CD18, required for CD177-PRTN3-mediated activation of TNF primed neutrophils (By similarity). May regulate phagocytosis-induced apoptosis in extravasated neutrophils (By similarity). May play a role in mast cell development (By similarity). Required with TYROBP/DAP12 in microglia to control production of microglial superoxide ions which promote the neuronal apoptosis that occurs during brain development (PubMed:18685038)..

C57BL/10 splenocytes

大鼠(Rat)

人(Human), 小鼠(Mouse) | 人(Human),小鼠(Mouse)

CD11b

Flow Cytometry: Human peripheral blood monocyte

150.0 KDa

Unconjugated

Rat IgG2b

重组抗体

kappa

Protein A purified

P49E24

此产品可替代 Ab093718

Whole IgG