Recombinant CD45RO Antibody

抗体

CD45RO单克隆抗体 | Anti-CD45RO抗体 | CD45RO抗体 | CD45RO鼠单抗

B220 | CD45 antigen | CD45R | CD45RO | EC 3.1.3.48 | L-CA | LY5 | protein tyrosine phosphatase, receptor type, C | receptor-type tyrosine-protein phosphatase C | T200 glycoprotein | T200 leukocyte common antigen | T200receptor type, c polypeptide | B220 a

Ab212153-10μg

10μg

无动物源

≥95%(SDS-PAGE)

-20°C储存,避免反复冻融

超低温冰袋运输

Store at 4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.

PBS, pH 7.4

Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor (PubMed:35767951). Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity). (Microbial infection) Acts as a receptor for human cytomegalovirus protein UL11 and mediates binding of UL11 to T-cells, leading to reduced induction of tyrosine phosphorylation of multiple signaling proteins upon T-cell receptor stimulation and impaired T-cell proliferation.

IL-2 dependent T cell line, CA1

小鼠(Mouse)

人(Human)

Human CD45RO

Flow Cytometry: Human peripheral blood lymphocytes

150 kDa

Unconjugated

Mouse IgG2a

重组抗体

kappa

Protein A purified

P08F59

Whole IgG