CXCR4/CD184 Mouse mAb (PE)

抗体

CXCR4/CD184抗体

WHIM | WHIMS1 | D2S201E | CD184 | chemokine (C-X-C motif) receptor 4 | chemokine (C-X-C motif), receptor 4 (fusin) | C-X-C chemokine receptor type 4 | CXCR4 | CXC-R4 | CXCR-4 | D2S201ESDF-1 receptor | FB22 | Fusin | HM89 | HM89NPYRL | HSY3RR | LAP3 | LAP-

Ab212930-100T

100T

已验证

5 μL/test

2-8°C储存,避光,禁止冷冻

冰袋运输

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300.

0.05% Proclin300

Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ions levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhance intracellular calcium ions and reduce cellular cAMP levels. Involved in haematopoiesis and in cardiac ventricular septum formation. Plays also an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Could be involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 X4 isolates and as a primary receptor for some HIV-2 isolates. Promotes Env-mediated fusion of the virus.

小鼠(Mouse)

人(Human)

CXCR4/CD184

Flow Cytometry: Jurkat

PE

Mouse IgG2a

单克隆抗体

kappa

Protein A/G purified

12G5

Blue Laser(488nm), Green Laser(532nm), Yellow-Green Laser(561nm)

575nm

Ex:565nm;Em:575nm

Whole IgG