Recombinant FAT10 Antibody

抗体

泛素D抗体 | 泛素D单克隆抗体 | 泛素D重组单克隆抗体 | FAT10重组单克隆抗体 | FAT10单克隆抗体 | FAT10抗体

Diubiquitin antibody | FAT10 antibody | GABBR1 antibody | UBD 3 antibody | Ubd antibody | UBD_HUMAN antibody | Ubiquitin D antibody | Ubiquitin like protein FAT10 antibody | Ubiquitin-like protein FAT10 antibody | Diubiquitin | FAT10 | FAT10diubiquitin |

Ab215127-10μl

10μl

重组

见COA

-20°C储存,避免反复冻融

超低温冰袋运输

Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

10mM PBS, 150mM NaCl, 50% Glycerol, 0.05% BSA, 0.02% Sodium azide, pH 7.4.

0.02% Sodium azide

Ubiquitin-like protein modifier which can be covalently attached to target protein and subsequently leads to their degradation by the 26S proteasome, in a NUB1L-dependent manner. Probably functions as a survival factor. Conjugation ability activated by UBA6. Promotes the expression of the proteasome subunit beta type-9 (PSMB9/LMP2). Regulates TNF-alpha-induced and LPS-mediated activation of the central mediator of innate immunity NF-kappa-B by promoting TNF-alpha-mediated proteasomal degradation of ubiquitinated-I-kappa-B-alpha. Required for TNF-alpha-induced p65 nuclear translocation in renal tubular epithelial cells (RTECs). May be involved in dendritic cell (DC) maturation, the process by which immature dendritic cells differentiate into fully competent antigen-presenting cells that initiate T cell responses. Mediates mitotic non-disjunction and chromosome instability, in long-term in vitro culture and cancers, by abbreviating mitotic phase and impairing the kinetochore localization of MAD2L1 during the prometaphase stage of the cell cycle. May be involved in the formation of aggresomes when proteasome is saturated or impaired. Mediates apoptosis in a caspase-dependent manner, especially in renal epithelium and tubular cells during renal diseases such as polycystic kidney disease and Human immunodeficiency virus (HIV)-associated nephropathy (HIVAN). Post-translational: Can be acetylated.

A synthetic peptide derived from human FAT10 (AA 100-165).

兔(Rabbit)

人(Human), 小鼠(Mouse) | 人(Human),小鼠(Mouse)

UBD

WB: Hep G2, MCF7, SH-SY5Y and NIH/3T3 cell lysates. IF/ICC: HeLa cells.

150 kDa

Unconjugated

Rabbit IgG

重组抗体

kappa

Protein A purified

Whole IgG