CD31 Mouse mAb

抗体

血小板内皮细胞黏附分子 | 血小板内皮细胞黏附分子抗体 | 血小板内皮细胞黏附分子小鼠单克隆抗体 | 小鼠抗人血小板内皮细胞黏附分子抗体 | CD31抗体 | PECAM1抗体

Adhesion molecule antibody | CD31 antibody | CD31 antigen antibody | CD31 EndoCAM antibody | EndoCAM antibody | FLJ34100 antibody | FLJ58394 antibody | GPIIA antibody | GPIIA' antibody | PECA1 antibody | PECA1_HUMAN antibody | Pecam 1 antibody | PECAM 1 C

Ab216301-10μl

10μl

无载体

≥95%(SDS-PAGE)

-20°C储存,避免反复冻融

超低温冰袋运输

Store at 4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.

PBS, pH 7.2

Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-690 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Trans-homophilic interaction may play a role in endothelial cell-cell adhesion via cell junctions. Heterophilic interaction with CD177 plays a role in transendothelial migration of neutrophils. Homophilic ligation of PECAM1 prevents macrophage-mediated phagocytosis of neighboring viable leukocytes by transmitting a detachment signal. Promotes macrophage-mediated phagocytosis of apoptotic leukocytes by tethering them to the phagocytic cells; PECAM1-mediated detachment signal appears to be disabled in apoptotic leukocytes. Modulates bradykinin receptor BDKRB2 activation. Regulates bradykinin- and hyperosmotic shock-induced ERK1/2 activation in endothelial cells. Induces susceptibility to atherosclerosis (By similarity).

Recombinant protein corresponding to Human CD31

小鼠(Mouse)

人(Human)

Human CD31

WB: HUVEC, THP-1 and Jurkat whole cell lysates

150.0 KDa

Unconjugated

Mouse IgG1

单克隆抗体

kappa

Protein A purified

AB02/2H10

Whole IgG