Lamin A/C Mouse mAb (AF488)

抗体

核纤层蛋白 | 核纤层蛋白A | 核纤层蛋白C | Anti- Lamin A/C抗体 | LMNA小鼠单克隆抗体 | Lamin A/C小鼠单克隆抗体 | Lamin A/C抗体；LMNA抗体

70 kDa lamin antibody | Cardiomyopathy dilated 1A (autosomal dominant) antibody | CDCD1 antibody | CDDC antibody | CMD1A antibody | CMT2B1 antibody | EMD2 antibody | FPL antibody | FPLD antibody | FPLD2 antibody | HGPS antibody | IDC antibody | Lamin A an

Ab219214-10μl

10μl

已验证

0.5 mg/mL

避光,-20°C储存,避免反复冻融

超低温冰袋运输

Store at -20°C. Protect from light. Avoid freeze/thaw cycles.

Liquid in PBS pH 7.4, containing 50% glycerol, 1% BSA and 0.05% Proclin300.

0.05% Proclin300

Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Play an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Prelamin-A/C can accelerate smooth muscle cell senescence. It acts to disrupt mitosis and induce DNA damage in vascular smooth muscle cells (VSMCs), leading to mitotic failure, genomic instability, and premature senescence .

Recombinant protein corresponding to Human Lamin A

小鼠(Mouse)

人(Human), 大鼠(Rat) | 人(Human),大鼠(Rat)

Lamin A

Flow Cytometry: HeLa cells ICC/IF: HeLa cells

AF488

Mouse IgG2b

单克隆抗体

kappa

Protein A purified

AB07/4G6

Blue Laser(488nm)

525nm

Ex:490nm;Em:525nm

Whole IgG