Mouse FcR Blocking Reagent

生物试剂/缓冲液

Fc受体阻断剂 | Fc受体封闭剂 | FcR阻断剂 | 小鼠Fc受体封闭剂 | FcγIII受体 | FcγII受体 | 白细胞分化抗原16 | 白细胞分化抗原32 | CD16/32抗体 | Fc受体阻断剂 | Fc受体封闭剂 | FcR阻断剂 | 小鼠Fc受体封闭剂

Fc block | Fc Receptor Blocker | FcR Blocking Reagent, mouse | Mouse Fc blocker | Fc receptor blocking antibody | Mouse Fc Receptor Blocking Solution | Fc Receptor Binding Inhibitor Antibody | anti-Mouse Fc Block Monoclonal Antibody | Fc Receptor Blocking

Ab219990-250μl

250μL

无动物源

≥95%(SDS-PAGE)

2-8°C储存,禁止冷冻

冰袋运输

Store at 4°C.

Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300.

0.05% Proclin300

CD16: Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor which binds to IgG1, IgG2a and IgG2b. Mediates neutrophil activation by IgG complexes redundantly with Fcgr4. CD32: Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of antigen-antibody complexes from the circulation and modulation of antibody production by B-cells. Isoform IIB1 and isoform IIB1' form caps but fail to mediate endocytosis or phagocytosis. Isoform IIB2 can mediate the endocytosis of soluble immune complexes via clathrin-coated pits. Isoform IIB1 and isoform IIB2 can down-regulate B-cell, T-cell, and mast cell activation when coaggregated to B-cell receptors for AG (BCR), T-cell receptors for AG (TCR), and Fc receptors, respectively.

Mouse BALB/c Macrophage J774

大鼠(Rat)

小鼠(Mouse)

Mouse CD16/CD32

Flow Cytometry: C57BL/6 mouse splenocytes

150 kDa

Unconjugated

Rat IgG2b

重组抗体

lambda

Protein A purified

P90A23

Whole IgG