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名称
CD47 Mouse mAb
分子类型
抗体
别名
白细胞表面抗原47 | CD47 抗体 | 白细胞表面抗原47抗体
英文别名
Antigen identified by monoclonal antibody 1D8 antibody | Antigenic surface determinant protein OA3 antibody | CD 47 antibody | CD47 antibody | CD47 antigen (Rh-related antigen, integrin-associated signal transducer) antibody | CD47 antigen antibody | CD47
货号
Ab220855-10μl
包装规格
10μl
级别
无载体
浓度
≥95%(SDS-PAGE)
储存温度
-20°C储存,避免反复冻融
运输条件
超低温冰袋运输
稳定性与储存
短期储存2-8℃ (1-2周); 长期储存-20℃ (24个月); 收货后建议分装,避免反复冻融.
储存缓冲液
PBS, pH 7.2
生化机理
Adhesive protein that mediates cell-to-cell interactions. Acts as a receptor for thrombospondin THBS1 and as modulator of integrin signaling through the activation of heterotrimeric G proteins Involved in signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, cellular self-renewal, and immunoregulation Plays a role in modulating pulmonary endothelin EDN1 signaling Modulates nitrous oxide (NO) signaling, in response to THBS1, hence playing a role as a pressor agent, supporting blood pressure Plays an important role in memory formation and synaptic plasticity in the hippocampus Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation Positively modulates FAS-dependent apoptosis in T-cells, perhaps by enhancing FAS clustering Plays a role in suppressing angiogenesis and may be involved in metabolic dysregulation during normal aging In response to THBS1, negatively modulates wound healing Inhibits stem cell self-renewal, in response to THBS1, probably by regulation of the stem cell transcription factors POU5F1/OCT4, SOX2, MYC/c-Myc and KLF4 May play a role in membrane transport and/or integrin dependent signal transduction May prevent premature elimination of red blood cells
免疫原
Recombinant protein corresponding to Human CD47
宿主种属
小鼠(Mouse)
种属反应性
人(Human)
特异性
Human CD47
阳性对照
Flow Cytometry: Jurkat cells
SDS-PAGE
150.0 KDa
偶联
Unconjugated
亚型
Mouse IgG1
克隆类型
单克隆抗体
轻链亚型
kappa
纯化方法
Protein A purified
克隆号
AB02/2F5
Format
Whole IgG
预测反应种属
Gorilla gorilla gorilla,Nomascus leucog,Nomascus leucogenys,Pan paniscus,Pan troglodytes,Pongo abelii,Pongo pygmaeus
危险属性
「暂无危险属性」
上下游信息
「暂无上下游信息」
技术文档
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相关文章
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CD47 Mouse mAb 无载体 10μl

品牌:阿拉丁
货号:Ab220855-10μl
级别: 无载体
货期:30天
已售 722 件
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运费:0 元
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10μl

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