Recombinant CD31 Antibody

抗体

血小板-内皮细胞黏附分子 | CD31抗体 | PECAM-1抗体 | 小鼠抗人CD31单克隆抗体

Adhesion molecule antibody | CD31 antibody | CD31 antigen antibody | CD31 EndoCAM antibody | EndoCAM antibody | FLJ34100 antibody | FLJ58394 antibody | GPIIA antibody | GPIIA' antibody | PECA1 antibody | PECA1_HUMAN antibody | Pecam 1 antibody | PECAM 1 C

Ab222916-10μg

10μg

无动物源

≥95%(SDS-PAGE)

-20°C储存,避免反复冻融

超低温冰袋运输

短期储存2-8℃（1-2周）；长期储存-20℃（24个月）；收货后建议分装，避免反复冻融.

PBS, pH 8.0

Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-690 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Trans-homophilic interaction may play a role in endothelial cell-cell adhesion via cell junctions. Heterophilic interaction with CD177 plays a role in transendothelial migration of neutrophils. Homophilic ligation of PECAM1 prevents macrophage-mediated phagocytosis of neighboring viable leukocytes by transmitting a detachment signal. Promotes macrophage-mediated phagocytosis of apoptotic leukocytes by tethering them to the phagocytic cells; PECAM1-mediated detachment signal appears to be disabled in apoptotic leukocytes. Modulates bradykinin receptor BDKRB2 activation. Regulates bradykinin- and hyperosmotic shock-induced ERK1/2 activation in endothelial cells. Induces susceptibility to atherosclerosis (By similarity). Isoform Delta15, Does not protect against apoptosis.

Human CD31

小鼠(Mouse)

人(Human)

Human CD31

Flow Cytometry: Human peripheral blood lymphocytes

150 kDa

Unconjugated

Mouse IgG1

重组抗体

kappa

Protein A purified

P19C27

Whole IgG