Recombinant CD11b Antibody (FITC)

抗体

CD11抗原样家族成员B | 整合素alpha M | CD11b抗体 | ITGAM抗体 | Anti-CD11b抗体 | 小鼠抗人CD11b抗体

antigen CD11b (p170) antibody | Antigen CD11b p170 antibody | CD11 antigen like family member B antibody | CD11 antigen-like family member B antibody | CD11b antibody | CD11b/CD18 antibody | CD49d antibody | Cell surface glycoprotein MAC-1 subunit alpha a

Ab223989-25T

25T

重组

5 μL/test

2-8°C储存,避光,禁止冷冻

冰袋运输

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300.

0.05% Proclin300

Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin ITGAM/ITGB2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. Regulates neutrophil migration. In association with beta subunit ITGB2/CD18, required for CD177-PRTN3-mediated activation of TNF primed neutrophils. May regulate phagocytosis-induced apoptosis in extravasated neutrophils (By similarity). May play a role in mast cell development (By similarity). Required with TYROBP/DAP12 in microglia to control production of microglial superoxide ions which promote the neuronal apoptosis that occurs during brain development (By similarity)

Human monocytes

小鼠(Mouse)

人(Human)

Human CD11b

FITC

Mouse IgG1

重组抗体

kappa

Protein A purified

P56E55

Blue Laser(488nm)

517nm

Ex:498nm;Em:517nm

Whole IgG