二苯甲基哌嗪

小分子

1-(二苯基甲基)哌嗪

CINNARIZINE IMPURITY A | 1-Benzhydryl piperazine | 1-diphenylmethylpiperazine | AC-15867 | Benzhydrylpiperazine; 1-Benzhydrylpiperazine; 1-(Diphenylmethyl)piperazine; 4-(Diphenylmethyl)piperazine; 4-Benzhydrylpiperazine; N-(Diphenylmethyl)piperazine | 4-(

1-Benzhydrylpiperazine

B134038-500g

500g

≥98%(GC)

2-8°C储存,充氩

冰袋运输

对空气敏感

1-(Diphenylmethyl)piperazine is an intermediate during drug synthesis. It has been reported to be formed during the oxidative metabolism of cinnarizine (CZ) [1-(diphenylmethyl)-4-(3-phenyl-2-propenyl)-piperazine] in rat liver microsomes.[1] It reacts with quinone in acetonitrile, followed by oxidation with an alkaline potassium ferricyanide, to afford 4-amino-3,6-di(tert-butyl)-o-benzoquinones. Application 1-(Diphenylmethyl)piperazine [N-(Diphenylmethyl)piperazine] may be used for the synthesis of 2-nitro-3,4,4-trichloro-1-(propylthio)-1-[4-(diphenylmethyl)piperazin-1-yl]-1,3-butadiene and 2-nitro-3,4,4-trichloro-1-(octadecylthio)-1-[4-(diphenylmethyl)piperazin-1-yl]-1,3-butadiene.

841-77-0

C17H20N2

252.36 g/mol

222773

MFCD00038379

70048

C1CN(CCN1)C(C2=CC=CC=C2)C3=CC=CC=C3

1-benzhydrylpiperazine

1S/C17H20N2/c1-3-7-15(8-4-1)17(16-9-5-2-6-10-16)19-13-11-18-12-14-19/h1-10,17-18H,11-14H2

NWVNXDKZIQLBNM-UHFFFAOYSA-N

C1CN(CCN1)C(C2=CC=CC=C2)C3=CC=CC=C3

504754480

可溶于甲苯

93 °C

1

2

3

252.163 Da

252.163 Da

15.300 Ų

19

0

230

0

1

2.8

115 °C

185 °C/2 mmHg

222773