Cucurbitacin E 是来自 Cucumic melo L 茎的一种天然化合物。Cucurbitacin E 显著抑制 cyclin B1/CDC2 复合物的活性。 Cucurbitacin E is a natural compound which from the climbing stem of Cucumic melo L. Cucurbitacin E significantly suppresses the activity of the cyclin B1/CDC2 complex. Cucurbitacin E has been used as a cofilin inhibitor, It is also used as a F-actin stabilizer to prevent membrane-associated periodic skeleton (MPS) loss and protect from axonal fragmentation.