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Taraxerol is isolated from Taraxacum mongolicum , and has anti-inflammtory and anti-cancer effects. Taraxerol attenuates acute inlammation through inhibition of NF-κB signaling pathway. Taraxerol induces cell apoptosis In Vitro Taraxerol (0-100 μM; 24 or 48 hours)significantly reduces cell viability to 95% (20 μM), 89.8% (40 μM), 82.6 % (60 μM), 72.9 % (80 μM), and 63.6% (100 μM).And this compound has cell viability of 90.7% at a concentration of 20 μM and 53.6% at the 100 μM concentration at 48 hours in Hela cells. Taraxerol (80 μM; 24 or 48 hours) induces Hela cells apoptosis and cell death in a dose-dependent manner.Taraxerol can induce a significant apoptosis of cells by annexin V/ PI double staining, significant increase in both the early (24.2%) and late (16.2%) stages of apoptotic cells compared with the control group at the early (6.5%) and late (0.5%) stages. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo Taraxerol (5 and 10mg/kg; i.p.) attenuates carrageenan induced paw edema 2h onward. The effect of taraxerol at the dose of 5mg/kg is found to be significant (p Form:Solid IC50& Target:IC50: apoptosis
中文名称
Taraxerol
英文名称
Taraxerol
中文别名
蒲公英赛醇
英文别名
alnulin | TARAXEROL [MI] | DTXSID001026552 | 27-Norolean-14-en-3-ol, 13-methyl-, (3beta,13alpha)- | skimmiol | BDBM50242128 | ISOOLEAN-14-EN-3beta-OL | AKOS032962064 | ISOOLEAN-14-EN-3.BETA.-OL | SCHEMBL569463 | NIOSH/AM5850000 | (3beta)-D-friedoolean-14-
CAS号
127-22-0
分子式
C30H50O
分子量
426.72 g/mol
精确质量
≥98%
PSA
20.200 Ų
Logp
9.300
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蒲公英赛醇

源叶 蒲公英赛醇 HPLC≥98% 20mg,127-22-0,规格齐全,生产科研实验检测,科学材料数智化一站式易购平台。

品牌:源叶
货号:B20938
级别: HPLC≥98%
货期:30天
已售 51 件
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