(2S)-6-Prenylnaringenin is the most efficient compound in forebrain. (2S)-6-Prenylnaringenin acts as a GABA A positive allosteric modulator at α+β- binding interface. In Vitro (2S)-6-Prenylnaringenin (6-Prenylnaringenin) displays a modulatory activity at low micromolar concentrations. (2S)-6-Prenylnaringenin potentiates GABA-induced displacement of [ 3 H]EBOB binding in a concentration-dependent manner where the IC 50 value for this potentiation in native GABAA receptors is 3.7 μM, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid