BRCA1-IN-2

BRCA1-IN-2

B646470-5mg

5mg

≥98%

-20°C储存

超低温冰袋运输

BRCA1-IN-2 (compound 15) is a cell-permeable protein-protein interaction (PPI) inhibitor for BRCA1 with an IC 50 of 0.31 μM and a K d of 0.3 μM, which shows antitumor activities via the disruption of BRCA1 (BRCT) 2 /protein interactions Form:Solid IC50& Target:IC50: 0.31 μM (BRCA1), Kd: 0.3 μM (BRCA1)

BRCA1-IN-2（化合物 15）是一种细胞渗透性蛋白-蛋白相互作用（PPI）抑制剂，其 IC 50 为 0.31 μM，K d 为 0.3 μM，通过破坏 BRCA1 (BRCT) 2 与蛋白的相互作用而显示出抗肿瘤活性。

1622262-55-8

C26H33N4O7P

544.54 g/mol

102369451

C1=CC=C(C=C1)CCCCNC(=O)CNC(=O)[C@H](COP(=O)(O)O)NC(=O)CCC2=CNC3=CC=CC=C32

[(2S)-2-[3-(1H-indol-3-yl)propanoylamino]-3-oxo-3-[[2-oxo-2-(4-phenylbutylamino)ethyl]amino]propyl] dihydrogen phosphate

1S/C26H33N4O7P/c31-24(14-13-20-16-28-22-12-5-4-11-21(20)22)30-23(18-37-38(34,35)36)26(33)29-17-25(32)27-15-7-6-10-19-8-2-1-3-9-19/h1-5,8-9,11-12,16,23,28H,6-7,10,13-15,17-18H2,(H,27,32)(H,29,33)(H,30,31)(H2,34,35,36)/t23-/m0/s1

TYEYIJQDNULZJQ-QHCPKHFHSA-N

C1=CC=C(C=C1)CCCCNC(=O)CNC(=O)C(COP(=O)(O)O)NC(=O)CCC2=CNC3=CC=CC=C32

102369451

DMSO : 100 mg/mL (183.64 mM; Need ultrasonic)