Brofaromine

小分子

溴法罗明

Brofaromine

B649069-5mg

5mg

≥98%

-20°C储存

超低温冰袋运输

Brofaromine (CGP 11305A) is a monoamine oxidase ( MAO ) inhibitor with IC 50 of 0.2 μM for MAO-A . In Vitro In order to assess whether the protective effect is related to the inhibition of the MAO-A or due to another mechanism, the effect of Brofaromine (CGP 11305A, BRO) is determined on the activity of MAO-A in cultured cortical cells. It shows, firstly, that cultured cortical cells have a significant MAO-A activity, and secondly, that Brofaromine inhibits the enzyme in a concentration-dependent manner. The IC 50 is 0.19 μM for Brofaromine . Hill coefficient is 0.96. The enzyme is almost completely inhibited at 10 μM . Brofaromine inhibits MAO-A activity of our cultured cortical cells in a concentration-dependent manner. The IC 50 range of Brofaromine is 0.01 μM to 0.1 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:IC50: 0.2 μM (MAO-A)

布罗法罗明（CGP 11305A）是一种单胺氧化酶（MAO）抑制剂，对 MAO-A 的 IC 50 为 0.2u2009μM。

63638-91-5

C14H16BrNO2

310.19 g/mol

44571

COC1=CC(=C2C(=C1)C=C(O2)C3CCNCC3)Br

COC1=CC(=C2C(=C1)C=C(O2)C3CCNCC3)Br

44571

DMSO : 250 mg/mL (805.96 mM; Need ultrasonic)

1

3

2

309.036 Da

309.036 Da

34.400 Ų

18

0

283.000

0

1

3.100