BPR1M97

BPR1M97

B649305-5mg

5mg

≥98%

-20°C储存

超低温冰袋运输

BPR1M97 is a dual-acting mu opioid receptor (MOP) and nociceptin-orphanin FQ peptide (NOP) receptor agonist with K i values of 1.8 and 4.2 nM, respectively. BPR1M97 shows high potency and blood-brain barrier penetration, and produces potent antinociceptive effects In Vivo BPR1M97 (1.8 mg/kg; s.c.; once) demonstrates antinociception in a murine model of cancer pain . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Male wild-type C57BL/6 mice (25-30 g) Dosage: 1.8 mg/kg Administration: Subcutaneous injection (s.c.); once Result: Demonstrated antinociception in a murine model of cancer pain. Form:Solid IC50& Target:Ki: 1.8 nM (MOP), 4.2 nM (NOP)

BPR1M97 是一种双效μ阿片受体（MOP）和神经肽-orphanin FQ 肽（NOP）受体激动剂，其 K i 值分别为 1.8 和 4.2 nM。BPR1M97 具有很高的药效和血脑屏障穿透性，可产生强效的抗镇痛作用。

2059904-66-2

C18H18Cl2N2O

349.25 g/mol

O=C(NCC1N(C)CCC2=C1C=CC=C2)C3=CC=C(Cl)C(Cl)=C3

DMSO : 250 mg/mL (715.82 mM; Need ultrasonic)