BIIL-260 hydrochloride

BIIL-260盐酸盐

BIIL-260 hydrochloride

B654923-1ml

1ml

10mM in DMSO

干燥,-80℃储存

超低温冰袋运输

BIIL-260 hydrochloride is a potent and long-acting orally active leukotriene B(4) receptor LTB 4 antagonist, with anti-inflammatory activity. BIIL-260 hydrochloride interacts with the LTB 4 receptor in a saturable, reversible, and competitive manner, has high affinity to the LTB 4 receptor on isolated human neutrophil cell membranes with K i values of 1.7 nM In Vitro BIIL-260 hydrochloride potently inhibits LTB 4 -induced intracellular Ca 2+ release in human neutrophils with IC 50 value of 0.82 nM MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:Ki: 1.7 nM (LTB 4 receptor)

盐酸 BIIL-260 是一种强效长效口服活性白三烯 B（4）受体 LTB 4 拮抗剂，具有抗炎活性。BIIL-260 盐酸盐能以可饱和、可逆和竞争性的方式与 LTB 4 受体相互作用，具有抗炎活性。

192581-24-1(DMSO)

C30H31ClN2O3

503.03 g/mol

CC(C)(C1=CC=C(C=C1)O)C2=CC=C(C=C2)OCC3=CC=CC(=C3)COC4=CC=C(C=C4)C(=N)N.Cl