Brofaromine

溴法罗明

Brofaromine

B655691-1ml

1ml

10mM in DMSO

-80℃储存

超低温冰袋运输

Brofaromine (CGP 11305A) is a monoamine oxidase ( MAO ) inhibitor with IC 50 of 0.2 μM for MAO-A . In Vitro In order to assess whether the protective effect is related to the inhibition of the MAO-A or due to another mechanism, the effect of Brofaromine (CGP 11305A, BRO) is determined on the activity of MAO-A in cultured cortical cells. It shows, firstly, that cultured cortical cells have a significant MAO-A activity, and secondly, that Brofaromine inhibits the enzyme in a concentration-dependent manner. The IC 50 is 0.19 μM for Brofaromine . Hill coefficient is 0.96. The enzyme is almost completely inhibited at 10 μM . Brofaromine inhibits MAO-A activity of our cultured cortical cells in a concentration-dependent manner. The IC 50 range of Brofaromine is 0.01 μM to 0.1 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:IC50: 0.2 μM (MAO-A)

布罗法罗明（CGP 11305A）是一种单胺氧化酶（MAO）抑制剂，对 MAO-A 的 IC 50 为 0.2u2009μM。

63638-91-5(DMSO)

C14H16BrNO2

310.19 g/mol

BrC1=CC(OC)=CC2=C1OC(C3CCNCC3)=C2