(±)-BI-D

(±)-BI-D

B656858-1ml

1ml

10mM in DMSO

-80℃储存

超低温冰袋运输

(±)-BI-D is a potent ALLINI(An allosteric IN inhibitor) that binds integrase at the LEDGF/p75 binding site.IC50 value: 2.4–2.9 μM(HIV-Luc infection of WT and Hdgfrp2 KO cells) Target: integrase inhibitorin vitro: Approximately 2.4–2.9 μM of BI-D was required to inhibit 50% of HIV-Luc infection of WT and Hdgfrp2 KO cells, while the IC50 decreased dramatically, to 160–200 nM, in Psip1 and double-KO cells.

(±)-BI-D是一种强效的ALLINI（异位IN抑制剂），能在LEDGF/p75结合位点与整合酶结合：约为 2.4-2.9 μM 的 BI-D

1416258-16-6(DMSO)

C25H27NO4

405.49 g/mol

OC(C(OC(C)(C)C)C1=C(C(C=CC=C2)=C2N=C1C)C3=CC(CCCO4)=C4C=C3)=O