厄洛替尼-d6，盐酸盐可有效抑制培养的人头和颈部肿瘤细胞中的EGFR自磷酸化，该细胞系表现出高水平的EGFR。厄洛替尼-d6 HCl还抑制PC-9细胞系的增殖，其中PC-9细胞系的EGFR基因外显子19含有缺失突变。厄洛替尼-d6 HCl和雷帕霉素的组合对细胞生长产生协同抑制作用。 Erlontinib-d6 hydrochloride potently inhibits EGFR autophosphorylation in cultured human head and neck tumor cells, a cell line which exhibits high levels of EGFR. Erlotinib-d6 HCl also inhibits the proliferation of PC-9 cell lines, which contain a deletion mutation on exon 19 of the EGFR gene. A combination of Erlotinib-d6 HCl and rapamycin produced a synergistic inhibitory effect on cell growth. Erlotinib-d6, Hydrochloride Saltis a labeled form of Erlontinib HCl, a potent EGFR autophosphorylation inhibitior