二十碳五烯酸-d5是一种氘化的ω-3脂肪酸，可在海洋生物中大量使用，并且与花生四烯酸相比，分别以大约5％和30％的比率被COX-1和COX-2氧化。它旨在用作通过GC或LC质谱法定量EPA的内标。二十碳五烯酸-d5也是5-LO的抑制剂。 Eicosapentaenoic Acid-d5 is a deuterated ω-3 fatty acid abundantly available in marine organisms and is oxygenated by COX-1 and COX-2 at rates of about 5% and 30%, respectively, compared to arachidonic acid. It is intended for use as an internal standard for the quantification of EPA by GC- or LC-mass spectrometry. Eicosapentaenoic Acid-d5 is also an inhibitor of 5-LO.