2-Chloroethyl isocyanate may be used in the synthesis of: • 8-carbamoyl-3-(2-chloroethyl)imidazo[5,1-d]-l,2,3,5-tetrazin-4(3H)-one • 1-(2-chloroethyl)-3-(2-hydroxyethyl) urea • 3-substituted 1-(2-chloroethyl)-3-β-glycosylureas • 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) • (2-chloroethyl)-4-acetoxybenzyl ester 2-Chloroethyl isocyanate may be used in the synthesis of: • 8-carbamoyl-3-(2-chloroethyl)imidazo[5,1-d]-l,2,3,5-tetrazin-4(3H)-one • 1-(2-chloroethyl)-3-(2-hydroxyethyl) urea • 3-substituted 1-(2-chloroethyl)-3-β-glycosylureas • 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) • (2-chloroethyl)-4-acetoxybenzyl ester