胆固醇酯酶 来源于假单胞菌

甾醇酯酰水解酶

C139684-25KU

25KU

EnzymoPure™

＞15U/mg

The enzyme is found primarily in pancreas and pancreatic secretions, but in other tissues as well. Bile salts, such as cholate and its conjμgates, act as stabilizers of the native polymeric form of the enzyme and can protect it from proteolytic degradation in the intestine.来自 荧光假单胞菌 的胆固醇酯酶已用于含胆固醇氧化酶的酶促胆固醇试剂组分的优化研究。荧光假单胞菌产生的胆固醇酯酶也用于研究脂解制剂酯酶活性的非变性蛋白质电转移。 该酶广泛应用于诊断实验室血清胆固醇的测定。 The enzyme is found primarily in pancreas and pancreatic secretions, but in other tissues as well. Bile salts, such as cholate and its conjugates, act as stabilizers of the native polymeric form of the enzyme and can protect it from proteolytic degradation in the intestine.

胆固醇酯酶（CE）是一种可逆酶，可以水解或合成胆固醇和其他固醇的脂肪酸酯。水不溶性长链脂肪酸酯的水解需要经过胆盐活化。短链脂肪酸和溶血磷脂的水溶性酯的水解则不需要胆盐的活化。它还可水解三、二和单酰基甘油、磷脂、溶血磷脂和神经酰胺。该酶在脂质和脂蛋白代谢以及动脉粥样硬化中可能具有多种功能。