Chebulagic acid

诃子酸

Chebulagic acid

C656833-1ml

1ml

10mM in DMSO

-80℃储存

超低温冰袋运输

Chebulagic acid is a COX-LOX dual inhibitor isolated from the fruits of Terminalia chebula Retz, on angiogenesis. Chebulagic acid is a M2 serine to asparagine 31 mutation (S31N) inhibitor and influenza antiviral. Chebulagic acid also against SARS-CoV-2 viral replication with an EC 50 of 9.76 μM. In Vitro Chebulagic acid can enhance the autophagy. Chebulagic acid exert anti-inflammatory and anti-infective effects. Chebulagic acid also shows a protective effect against 1-methyl-4-phenylpyridinium (MPP+)-induce cytotoxicity which mimics the pathological symptom of Parkinson's disease. Chebulagic acid inhibits the LPS-induced upregulation of TNF-α and IL-1β in a dose- and time-dependent manner. Furthermore, LPS-activated MAPK signaling is inhibited by Chebulagic acid treatment in the EA.hy926 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

诃子鞣酸是从诃子果实中分离出来的一种 COX-LOX 双重抑制剂，对血管生成有抑制作用。诃子鞣酸是一种 M2 丝氨酸到天冬酰胺 31 突变（S31N）抑制剂和流感抗病毒剂。诃子酸还能抗 SARS-CoV-2 病毒。

23094-71-5(DMSO)

C41H30O27

954.66 g/mol

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