Cyclic ADP-​ribose ammonium

环状 ADP-核糖铵

Cyclic ADP-​ribose ammonium

C658637-500μg

500μg

≥99%

-20°C储存,干燥

超低温冰袋运输

Cyclic ADP-ribose ammonium (cADPR ammonium) is a potent second messenger for calcium mobilization that is synthesized from NAD + by an ADP-ribosyl cyclase. Cyclic ADP-ribose ammonium increases cytosolic calcium mainly by Ryanodine receptor -mediated relea Appearance:Solid IC50& Target:Calcium mobilization TRPM2 channels Endogenous metabolite In Vitro:cADPR (20 nM) elicits a large rapid Ca 2+ release in sea urchin eggs homogenates. cADPR (100 µM; 10 min) induces a sustained elevation of intracellular calcium concentration in a subset (64%) of cultured astrocytes. cADPR (100 µM) and heat (35-3 In Vivo:cADPR (100 µM; push-pull type of brain microperfusion) elevats OT concentrations in ordinate or subordinate mice. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Biological Activity:Cyclic ADP-ribose ammonium (cADPR ammonium) is a potent second messenger for calcium mobilization that is synthesized from NAD + by an ADP-ribosyl cyclase. Cyclic ADP-ribose ammonium increases cytosolic calcium mainly by Ryanodine receptor -mediated relea

C15H21N5O13P2.xNH3

O[C@H]([C@@H]1O)[C@](O[C@]1([H])COP(O)(OP(O)(OC2)=O)=O)([H])N3C(N=CN([C@]4([H])O[C@@]2([H])[C@@H](O)[C@H]4O)C5=N)=C5N=C3.N.[x]