Cyclo(Arg-Gly-Asp-D-Phe-Cys) TFA

环(精氨酸-甘氨酸-天冬氨酸-D-苯丙氨酸-半胱氨酸)三氟乙酸

Cyclo(Arg-Gly-Asp-D-Phe-Cys) TFA

C658803-5mg

5mg

≥98%

避光,充氩,干燥,-80℃储存

超低温冰袋运输

Cyclo(Arg-Gly-Asp-D-Phe-Cys) (Cyclo RGDfC) TFA, a cyclic RGD peptide which has high affinity to αvβ3 , can disrupt cell integrin interactions. Cyclo(Arg-Gly-Asp-D-Phe-Cys) TFA inhibits pluripotent marker expression in embryonic stem cells (ESCs) and the t Appearance:Solid IC50& Target:αvβ3 In Vitro:Cyclo(Arg-Gly-Asp-D-Phe-Cys) TFA (0.5 mM; 24 h) down-regulates the transcription factors Oct 4, Sox 2 and Nanog of mESCs. Cyclo(Arg-Gly-Asp-D-Phe-Cys) TFA (0.5 mM) inhibits integrin gene expression mESC-col I (type I collagen) constructs. Cyclo( In Vivo:Cyclo(Arg-Gly-Asp-D-Phe-Cys) TFA (0.5 mM, 24 h)-treated mESCs in the presence/absence of Leukemia inhibitory factor (LIF) (injected in both thighs) generated teratomas in severe combined immunodeficiency (SCID) mice, which indicates that the process of mE Biological Activity:Cyclo(Arg-Gly-Asp-D-Phe-Cys) (Cyclo RGDfC) TFA, a cyclic RGD peptide which has high affinity to αvβ3 , can disrupt cell integrin interactions. Cyclo(Arg-Gly-Asp-D-Phe-Cys) TFA inhibits pluripotent marker expression in embryonic stem cells (ESCs) and the t

C26H35F3N8O9S

692.66 g/mol

H2O : 5 mg/mL (7.22 mM; Need ultrasonic)