Dibenzocycolctyne PEG 硅烷

DBCO PEG Silane

D163540-10mg

10mg

MW 3400 Da

避光,-20°C储存,充氩

超低温冰袋运输

对光线敏感

DBCO (dibenzocycolctyne) PEG Silane derivatives can go Click Chemistry reaction without a need of any metal catalysts. The strain-promoted 1,3-dipolar cycloaddition of cyclooctynes and azides, also termed as the Cu-free click reaction, is a bioorthogonal reaction that enables the conjugation of two molecules in aqueous solution. DBCO PEG derivatives possess fast kinetics and stability in aqueous buffer. DBCO reagents can be used to label azide-modified biomolecules spontaneous without the need for toxic Cu catalysts. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.