DCP-LA是选择性的PKC-ε（PKC-ε）激活剂。在采用反相高效液相色谱的原位| PKC分析中，DCP-LA以浓度（10 nM-100μM）依赖性的方式显着激活PC-12细胞中的PKC，在100 nM时效果最大。 。与其他PKC同工酶相比，DCP-LA激活PKC-ε的效力提高了7倍。 DCP-LA (FR236924), a linoleic acid derivative, selectively and directly activates PKCε. DCP-LA activates Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) and inhibits protein phosphatase-1 (PP-1) to stimulate AMPA receptor exocytosis. DCP-LA inhibits activation of caspase-3/-9 and protects neurons at least in part from oxidative stress-induced apoptosis.