DBCO-NHCO-PEG4-acid 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。 DBCO-NHCO-PEG4-acid is an analog of DBCO-Acid with a hydrophilic PEG spacer arm, which improves water solubility. This reagent is a non-activated building block with enhanced solubility in aqueous media and can thus be used to derivatize amine-containing molecule through a stable amide bond. DBCO is commonly used for copper-free Click Chemistry reactions.