DBCO-PEG6-amine 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。DBCO-PEG6-amine 是一种点击化学试剂。它含有 DBCO 基团，可以和含有 Azide 基团的分子发生环张力 (strain) 促进的炔-叠氮环加成反应 (SPAAC)。 DBCO-PEG6-amine is a PEG derivative which contains DBCO and amine moieties. The DBCO group is commonly used in copper-free Click Chemistry reactions. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydrophilic PEG spacer increases the water solubility of the compound.