Desmethyl cariprazine is an active metabolite of Cariprazine Cariprazine, an antipsychotic agent candidate, exhibits high affinity for the D3 (K i =0.085 nM) and D2 (0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (2.6 nM) . Form:Solid IC50& Target:D|3|Receptor|0.085 nM (Ki)|D|2|Receptor|0.49 nM (Ki)|5-HT|1A|Receptor|2.6 nM (Ki)