4,5-Dimethoxycanthin-6-one

小分子

4,5-二甲氧基肉桂酸-6-酮

4,5-Dimethoxycanthin-6-one

D648025-5mg

5mg

≥98%

2-8°C储存,避光

冰袋运输

4,5-Dimethoxycanthin-6-one is a potent and uncompetitive inhibitor of CYP1A2 -mediated phenacetin O-deethylation with an IC 50 value of 1.7μM and a K i value of 2.6 μM. 4,5-Dimethoxycanthin-6-one, as an alkaloid, is isolated from the wood of Picrasma quassioides BENNET (Simaroubaceae). In Vitro 4,5-Dimethoxycanthin-6-one is a potent and uncompetitive inhibitor of CYP1A2-mediated phenacetin O-deethylation with an IC 50 value of 1.7μM and a K i value of 2.6 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid

4,5-二甲氧基黄嘌呤-6-酮是 CYP1A2 介导的苯乙酸 O-脱乙基作用的一种强效非竞争性抑制剂，其 IC 50 值为 1.7 μM，K i 值为 2.6 μM。4,5-Dimethoxycanthin-6-one 作为一种生物碱，是从 Picrasma quas 的木材中分离出来的。

18110-87-7

C16H12N2O3

280.28 g/mol

638215

COC1=C(C(=O)N2C3=CC=CC=C3C4=C2C1=NC=C4)OC

COC1=C(C(=O)N2C3=CC=CC=C3C4=C2C1=NC=C4)OC

638215

DMSO : 10 mg/mL (35.68 mM; Need ultrasonic)

0

4

2

280.085 Da

280.085 Da

53.400 Ų

21

0

490

0

1

2.3