Dimethindene maleate is a selective histamine H1 antagonist with antihistamine effects. Dimethindene maleate can be used for the research of hypersensitivity reactions In Vitro Dimethindene maleate (1-1000 μM) suppresses the cromakalim-induced/glibenclamide-sensitive K ＋ currents in a concentration-dependent and reversible manner with an IC 50 value of 29.5 μM. Dimethindene maleate (1-1000 μM) inhibits Y-26763-induced glibenclamide-sensitive K ＋ currents with an IC 50 value of 49 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo Dimethindene maleate (0.25 mg; i.p. once) affects wound healing in mice . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: C57BL/6 mice with wound healing Dosage: 0.25 mg Administration: Intraperitoneal injection; 0.25 mg once Result: Significantly delayed skin wound and only showed wound closure impairment in the initial phase wound healing. Form:Solid IC50& Target:IC50: 29.5 μM (cromakalim-induced K ＋ currents), 49 μM (Y-26763-induced K ＋ currents)