Deltasonamide 1 TFA is a PDE6δ-KRas inhibitor. Deltasonamide 1 can inhibit PDE6δ-KRas with a K D of 203 pM. Deltasonamide 1 can be used for the research of tumors In Vitro Deltasonamide 1 can inhibit PDE6δ-KRas with a K D of 203 pM. Deltasonamide 1 binds to PDE6δ with up to 7 hydrogen bonds, resulting in picomolar affinity. Deltasonamide 1 strongly reduces proliferation. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Proliferation AssayCell Line: RTCA of hPDAC cell lines Concentration: 0.375, 0.75, 1.5, 3, 6, 12 μM Incubation Time: 60 h Result: Inhibited proliferation of human pancreatic cancer cell lines. Form:Solid IC50& Target:KD: 203 pM (PDE6δ-KRas)