Duocarmycin TM

多卡米星

Duocarmycin TM

D656393-1ml

1ml

10mM in DMSO

-80℃储存

超低温冰袋运输

Duocarmycin TM (CBI-TMI) is a potent antitumor antibiotic . Duocarmycin TM induces a sequence-selective alkylation of duplex DNA. In Vitro Duocarmycin TM (60 μM; 4 d; BJAB and WSU-DLCL2 cells) is a cytotoxic agent that inhibits the proliferation of tumor cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability AssayCell Line: BJAB and WSU-DLCL2 cells Concentration: 60 μM Incubation Time: 4 days Result: Inhibited the proliferation of tumor cells with IC 50 values of 0.153 μM and 0.079μM for BJAB and WSU-DLCL2 cells, respectively. IC50& Target:Duocarmycins

Duocarmycin TM（CBI-TMI）是一种强效抗肿瘤抗生素。Duocarmycin TM 可诱导双链 DNA 发生序列选择性烷基化。

157922-77-5(DMSO)

C25H23ClN2O5

466.91 g/mol

COC1=C(C(=C2C(=C1)C=C(N2)C(=O)N3CC(C4=C3C=C(C5=CC=CC=C54)O)CCl)OC)OC