Dalazatide TFA

达拉扎肽TFA

Dalazatide TFA

D659042-5mg

5mg

≥98%

干燥,-80℃储存

超低温冰袋运输

Dalazatide (ShK-186) TFA is a specific Kv1.3 potassium channel peptide inhibitor. Dalazatide TFA can be used in the study of autoimmune diseases such as multiple sclerosis (MS), lupus erythematosus, psoriasis, rheumatoid arthritis, type 1 diabetes and inf Appearance:Solid IC50& Target:Kv1.3 In Vitro:Dalazatide (ShK-186) (0-1000 pM) TFA blocks the Kv1.3 current in the Ova-specific GFP+ effector memory T (Tem) cells in a dose-dependent manner with a K d of 65 ± 5 pM. Dalazatide (0-100 nM; 3 days) TFA inhibits CCR7 − T cell proliferation in a dose- In Vivo:Dalazatide (ShK-186) (100 μg/kg; s.c.; once) TFA inhibits delayed-type hypersensitivity and suppresses the in vivo motility and activation of Tem cells in rats. MCE has not independently confirmed the accuracy of these methods. They are for reference Biological Activity:Dalazatide (ShK-186) TFA is a specific Kv1.3 potassium channel peptide inhibitor. Dalazatide TFA can be used in the study of autoimmune diseases such as multiple sclerosis (MS), lupus erythematosus, psoriasis, rheumatoid arthritis, type 1 diabetes and inf

C186H297F3N57PS7

4556.1 g/mol

H2O Peptide Solubility and Storage Guidelines: 1.Calculate the length of the peptide. 2.Calculate the overall charge of the entire peptide according to the following table: Contents Assign value Acidic amino acid Asp (D), Glu (E),