DP-C-4

DP-C-4

D659219-5mg

5mg

≥99%

充氩,-80℃储存

超低温冰袋运输

DP-C-4 is a Cereblon -based dual PROTAC for simultaneous degradation of EGFR and PARP. Appearance:Solid IC50& Target:Cereblon In Vitro:DP-C-4 (1-50 μM; 24 hours) has degradation effects on EGFR and PARP simultaneously in a dose-dependent manner in SW1990 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Western Blot AnalysisC Biological Activity:DP-C-4 is a Cereblon -based dual PROTAC for simultaneous degradation of EGFR and PARP.

C72H78ClF2N15O14

1450.93 g/mol

O=C1NN=C(CC2=CC=C(F)C(C(N3CCN(C(CCCCCNC(C(NC(CCCCCOC4=C(OC)C=C(N=CN=C5NC6=CC=C(F)C(Cl)=C6)C5=C4)=O)COCC7=CN(CCOCCOCCNC8=CC=CC(C(N9C%10CCC(NC%10=O)=O)=O)=C8C9=O)N=N7)=O)=O)CC3)=O)=C2)C%11=C1C=CC=C%11

DMSO : 12 mg/mL (8.27 mM; Need ultrasonic)