2,6-Dichloro-3-nitropyridine undergoes macrocyclic condensation reaction with resorcinol derivatives to yield chiral tetraoxacalix[2]arene[2]pyridines2,6-Dichloro-3-nitropyridine was used: · in the synthesis of pyridyldifluoroacetates · as starting reagent in the preparation of bicyclooxacalixhetarene 2,6-Dichloro-3-nitropyridine undergoes macrocyclic condensation reaction with resorcinol derivatives to yield chiral tetraoxacalix[2]arene[2]pyridines