1.Palladium-catalyzed coupling reactions. 2.Preparation of benzopyranone derivatives as positive GABAA receptor modulators. 3.Preparation of aryl alkenes via three-component coupling catalyzed by palladium. 4.Suzuki-Miyaura coupling. 5.Rhodium catalyzed cyanation with N-cyano-N-phenyl-p-methylbenzenesulfonamide. 6.Preparation of bisphosphonate inhibitors of human farnesyl pyrophosphate synthase. application： 3,5-Dimethoxybenzeneboronic acid is used as reactant for palladium-catalyzed coupling reactions, preparation of benzopyranone derivatives as positive GABAA receptor modulators, preparation of aryl alkenes via three-component coupling catalyzed by palladium and Suzuki-Miyaura coupling. It is also used as reactant for rhodium catalyzed cyanation with N-cyano-N-phenyl-p-methylbenzenesulfonamide and preparation of bisphosphonate inhibitors of human farnesyl pyrophosphate synthase.