Dipeptidyl Peptidase VII human

D755256-10μg

10μg

重组

expressed in Sf9 cells

Dipeptidyl Peptidase VII (DPP7), also known as DPP2 or quiescent cell proline dipeptidase, is a post-proline cleaving aminopeptidase that is expressed in quiescent lymphocytes . DPP7 is used to study the regulation of cell quiescence . Like DPP4, DPP7 may be useful in diabetes and vascular disease research . Dipeptidyl Peptidase VII (DPP7), also known as DPP2 or quiescent cell proline dipeptidase, is a post-proline cleaving aminopeptidase that is expressed in quiescent lymphocytes . DPP7 is used to study the regulation of cell quiescence . Like DPP4, DPP7 may be useful in diabetes and vascular disease research .

DPP7 对维持淋巴细胞和成纤维细胞处于 G（0）状态至关重要。 抑制 DPP7 会导致细胞凋亡，而细胞凋亡是由 c-Myc 和 p53 的诱导介导的 。 DPP7 与脯氨酰羧肽酶有很强的序列同源性，在酸性和中性 pH 下均有活性。